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Best peptide for weight loss – retatrutide

best peptide for weight loss

Best peptide for weight loss – retatrutide

Through 26 experiments, a study involving 15500 participants showed that retatrutide is best peptide for weight loss.

Research use peptide for weight loss drug retatrutide mimics three hormones. It can help obese adults lose 24.2% of their weight within 48 weeks. Superior to treatment methods approved by the US Food and Drug Administration, such as Ozempic and Wegovy.

How does Retatrutide work?

Retatrutide is a weekly experimental injectable drug developed by Eli Lilly.

It is a three receptor agonist, which means it activates three key hormone pathways that play a role in glucose metabolism and appetite regulation:

Glucagon like peptide-1 (GLP-1) receptor – involved in insulin secretion, appetite suppression, and slowed digestion.
Glucose dependent insulinotropic polypeptide (GIP) receptor – enhances insulin release upon food intake, which may help with weight loss.
Glucagon receptors play an important role in energy expenditure and fat metabolism.
This multi receptor action distinguishes retatrutide from existing GLP-1 receptor agonists such as semaglutide (Ozempic or Wegovy) and dual agonists such as tirzepatide (Mounjaro or Zepbond).

Clinical trials results

In the SURMOUNT-1 Trial (a study on obesity), participants lost up to 24.2% of their body weight over 48 weeks – the most significant weight reduction seen in an anti-obesity medication to date. Higher doses of retatrutide resulted in greater weight loss. Retatrutide is the best peptide for weight loss.
In type 2 diabetes trials, retatrutide significantly reduced HbA1c levels, with some participants achieving near-normal glucose levels. The combination of GLP-1, GIP and glucagon receptor activation provided superior glycemic control compared to existing GLP-1-based therapies.

 

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